| Cat. No. |
Product Name |
Information |
| PC-21265 |
Feeblin
IRF5 inhibitor
|
Feeblin (SLC15A4 inhibitor C5) is a small molecule inhibitor of the proinflammatory TLR7/8/9-IRF5 pathway (IC50=1.6 uM) by disrupting the SLC15A4-TASL adapter module, Feeblin is an IRF5 pathway-specific inhibitor. |
| PC-21240 |
NOX-6-7
GPR132 agonist
|
NOX-6-7 is a potent, selective GPR132 agonist with EC50 of 44 nM. |
| PC-21239 |
NOX-6-18
GPR132 inhibitor
|
NOX-6-18 is a potent, selective GPR132 antagonist with IC50 of 17 nM. |
| PC-21213 |
YL-365
GPR34 inhibitor
|
YL-365 (YL365) is a highly potent, selective and competitive antagonist of GPR34. |
| PC-21184 |
UGT8 inhibitor 19
UGT8 inhibitor
|
UGT8 inhibitor 19 is a highly potent, selective and orally active ceramide galactosyltransferase enzyme UGT8 inhibitor with IC50 of 0.2 nM. |
| PC-21142 |
(3S) ALG-05
TILs inhibitor
|
(3S) ALG-05 is a potent pan-inhibitor of gut microbia tryptophan-indole-lyases (TILs, E.C. 4.1.99.1), exhibits inhibitory activity across TILs with Ki of 7-11 uM. |
| PC-21113 |
VJDT
TREM1 inhibitor
|
VJDT (TREM1 inhibitor) is a novel small molecule inhibitor of triggering receptor expressed on myeloid cell 1 (TREM1), effectively blocks TREM1 signaling. |
| PC-21054 |
SOFTI
SPINDLY inhibitor
|
SOFTI is a small molecule inhibitor of O-fucosyltransferase SPINDLY (SPY) with IC50 of 13.32 uM, binds to the GDP-fucose-binding pocket of SPY and competitively inhibits GDP-fucose binding. |
| PC-21015 |
YB-537
Quinone reductase 2 inhibitor
|
YB-537 (YB537) is a potent, highly specific quinone reductase 2 (QR2) inhibitor with IC50 of 3 nM, shows no activity against QR1 (IC50>10 uM). |
| PC-21002 |
FDW028
FUT8 inhibitor
|
FDW028 is a potent and highly selective small-molecule inhibitor of fucosyltransferase 8 (FUT8) with binding KD value of 5.486 uM, displays no affinity against other FUTs, shows potent anti-CRC activities. |
| PC-20817 |
KZR-8445
Sec61 inhibitor
|
KZR-8445 (KZR8445) is a cyclic depsipeptide, client-selective Sec61 inhibitor with IC50 of 100 nM, targets the Sec61 translocon and selectively modulate Sec61-mediated protein biogenesis. |
| PC-20785 |
Sodium phytate
|
Sodium phytate (Phytic acid sodium salt, InsP6 sodium) is the most abundant inositol phosphate in cells, is a strong inhibitor of iron absorption from fortified foods, has antioxidant and anti-diabetic properties. |
