| Cat. No. |
Product Name |
Information |
| PC-21807 |
RU-NT-206
Ricin inhibitor
|
RU-NT-206 is a small molecule inhibitor targeting the P-stalk binding pocket of ricin toxin A subunit (RTA) with IC50 of 7 uM, inhibits catalytic activity and protects cells against ricin and Stx2 holotoxins. |
| PC-21805 |
SPI-1477
Spt5-Pol II inhibitor
|
SPI-1477 (SPI-77) is a small molecule Spt5-Pol II complex inhibitor (SPI), selectively lowers mutant huntingtin gene (Htt) mRNA level with IC50 of 0.1 nM, without affecting WT Htt. |
| PC-21804 |
SPI-0324
Spt5-Pol II inhibitor
|
SPI-0324 (SPI-24) is a small molecule Spt5-Pol II complex inhibitor (SPI), selectively lowers mutant huntingtin gene (Htt) mRNA level with IC50 of 0.52 uM, without affecting WT Htt. |
| PC-21800 |
LY3509754
IL-17A inhibitor
|
LY3509754 is a potent, selective and oral small molecule inhibitor of IL-17A with high binding potency(KD=2.14 nM), dose-dependently prevents human IL-17A and IL-17AF from binding human IL-17RA. |
| PC-21786 |
UT-59
Scap inhibitor
|
UT-59 is a specific inhibitor of cholesterol-sensing membrane protein Scap, binds to Scap's cholesterol-binding site, blocks SREBP activation and inhibits lipid synthesis. |
| PC-21752 |
DHC-156
Brachyury inhibitor
|
DHC-156 is a covalent small molecule inhibitor of oncogenic transcription factor brachyury, selectively binds to brachyury, DHC-156 is potent brachyury downmodulator with DC50 of 4.1 uM. |
| PC-21744 |
G3BP inhibitor a
G3BP inhibitor
|
G3BP inhibitor a (G3Ia) is a specific, peptide mimetic inhibitor of RNA-binding proteins G3BP1/2 with SPR Kd value of 0.54 uM, blcoks the association of G3BP with its binding partners and inhibits condensation of G3BP both in vitro and in live cells. |
| PC-21742 |
Cypin inhibitor B9
Cypin inhibitor
|
Cypin inhibitor B9 is a small molecule cypin (cytosolic postsynaptic density protein 95 interactor) inhibitor, attenuates SCI-induced neuropathic pain, potentially by interfering with uric acid (UA) production. |
| PC-21741 |
GPR31 antagonist SAH2
GPR31 inhibitor
|
GPR31 antagonist SAH2 (SLU-0011371) is the first highly potent and selective small molecule GPR31 antagonist, antagonizes 12(S)-HETE-induced β-arrestin recruitment with IC50 of 1.09 uM. |
| PC-21728 |
Plitidepsin
eEF1A inhibitor
|
Plitidepsin (Aplidine) is a potent anti-cancer agent by targeting eEF1A2 with KD value of 80 nM, shows antiviral activity against SARS-CoV-2 with IC90 of 0.88 nM. |
| PC-21727 |
Didemnin B
eEF1A inhibitor
|
Didemnin B is selective eukaryotic elongation factor 1A1 (EEF1A1) inhibitor, Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. |
| PC-21725 |
A71915
NPRA inhibitor
|
A71915 is a highly potent and competitive natriuretic peptide receptor A (ANP, NPRA) antagonist with pKi of 9.18. |
