| Cat. No. |
Product Name |
Information |
| PC-63448 |
LBL1
|
LBL1 (Lamin A inhibitor LBL1) is a novel pyrroloquinazoline compound with significant anticancer activity, targets nuclear lamins and binds to the coiled-coil domain of lamin A (Kd=5.11 uM). |
| PC-63439 |
PH002
|
PH002 is a small-molecule structure corrector significantly decreased ApoE4 fragment levels in ApoE4/4-hiPSC-derived neurons, increases GABAergic neuron numbers and GAD67 levels, reduces p-tau levels, and decreases Aβ40 and Aβ42 production and/or secretion.. |
| PC-63371 |
Oxythiamine chloride hydrochloride
|
Oxythiamine chloride is a small molecule transketolase inhibitor with Kd of 33 nM, shows functional assay of human transketolase inhibition in HCT-116 cells with EC50 of 26 nM. |
| PC-63363 |
TMP-153
|
TMP-153 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor with IC50 of 5-10 nM for the hepatic and intestinal ACAT from various animals. |
| PC-63354 |
T-3861174
|
T-3861174 is a novel small molecule prolyl tRNA synthetase (PRS) with binding IC50 of 2.3 nM. |
| PC-63336 |
AZ-1355
|
AZ-1355 is an effctive lipid-lowering compound that inhibits platelet aggregation in vivo and elevates the prostaglandin I2/thromboxane A2 ratio in vitro.. |
| PC-63307 |
TLSC702
|
TLSC702 is a novel potent inhibitor of human glyoxalase I (hGLO I) with IC50 of 2.0 uM. |
| PC-63266 |
ABL127
|
ABL127 (ML174) is a potent, selective, covalent inhibitor of protein methylesterase 1 (PME-1) with IC50 of 10 nM. |
| PC-43424 |
NXY-059
|
NXY-059 (Disufenton sodium) is a free radical-trapping agent that demonstrates a considerable neuroprotective effect in vivo. |
| PC-43398 |
Avasimibe
|
Avasimibe (CI-1011, PD-148515) is a potent, selective inhibitor of acyl-CoA: cholesterol O-acyl transferase (ACAT) with IC50 of 60 nM. |
| PC-43358 |
SMND-309
|
SMND-309 is a derivate of salvianolic acid B, attenuates apoptosis and ameliorates mitochondrial energy metabolism in rat cortical neurons. |
| PC-43319 |
Laquinimod
|
Laquinimod (ABR-215062) is an immunoregulator derived from Linomide, has been shown to completely inhibit the development of murine acute experimental autoimmune encephalomyelitis (EAE). |
