| Cat. No. |
Product Name |
Information |
| PC-26113 |
JZ128
PKN3 inhibitor
|
JZ128 is a selective, covalent inhibitor of Protein Kinase N3 (PKN3) with IC50 of 120 nM, targets Cys840 in PKN3, has no activity against CDK7 or CDK12/13. |
| PC-26112 |
GSK902056A
PKN3 inhibitor
|
GSK902056A is a highly potent inhibitor of serine/threonine kinase PKN3 with Kdapp of 1 nM, potently engaged PKN3 in cells with IC50 of 79 nM. |
| PC-26108 |
Py-Pip
Neurolysin activator
|
Py-Pip is a nonpeptide small molecule activator of Neurolysin (Nln), enhances the activity of peptidase neurolysin. |
| PC-26095 |
Profilin1 inhibitor UP-6
Profilin1 inhibitor
|
Profilin1 inhibitor UP-6 is a specific small molecule inhibitor of Actin-binding protein profilin1 (Pfn1), inhibits Pfn1-actin interaction and tumor angiogenesis. |
| PC-26091 |
Etoxazole
Acaricide
|
Etoxazole (YI-5301) is a highly effective acaricide that affects the nymphs, eggs, and larvae of spider mites by inhibiting chitin biosynthesis. |
| PC-26087 |
MKV3
Cu+-ATPases inhibitor
|
MKV3 is a specific, first-in-class, broad spectrum inhibitor of Cu-transporting P-type ATPases targeting P1B-type copper ATPases, binds within the Cu+ entry pocket, thereby blocking Cu+ delivery to the intramembranous transport site, dependently decreases Cu+-stimulated ATPase activity with IC50 of 130 nM for Escherichia coli Cu+-ATPase CopA (EcCopA). |
| PC-26086 |
IDB-003
Translation inhibitor
|
IDB-003 is an orally active, unique context-dependent inhibitor of human translation that bind to the ribosome peptidyl transferase center (PTC) and inhibits elongation. |
| PC-26085 |
IDB-001
Translation inhibitor
|
IDB-001 is a small molecule, unique context-dependent inhibitor of human translation that bind to the ribosome peptidyl transferase center (PTC) and inhibits elongation. |
| PC-26079 |
TREM2 agonist S9
TREM2 agonist
|
TREM2 agonist S9 is a potent, small molecule Triggering receptor expressed on myeloid cells-2 (TREM2) agonist with MST binding KD of 0.95 uM. |
| PC-26078 |
HCY-NBD
GSTM2 stablizer
|
HCY-NBD is a small molecule stabilizer of Glutathione S-transferase Mu 2 (GSTM2), promotes sulfenylation at Cys174 of GSTM2 and inhibits its K48-linked ubiquitination at this residue, stabilizes GSTM2 protein levels. |
| PC-26076 |
ERX-208
LIPA inhibitor, ERS inducer
|
ERX-208 is a small molecule ERX-41 analog that binds stereospecifically to lysosomal acid lipase A (LIPA), induces endoplasmic reticulum stress (ERS) and apoptosis in a panel of OCa cell lines in vitro (IC50=100 nM). |
| PC-26063 |
Berberrubine chloride
TDP-43 aggregation inhibitor
|
Berberrubine chloride is an orally active metabolite of berberine, alleviates mucosal lesions and inflammation in mouse colitis models, inhibits TDP-43 aggregation and shows anti-inflammatory, anti-tumor, and antiviral activities. |
