| Cat. No. |
Product Name |
Information |
| PC-63248 |
BI-1935
sEH inhibitor
|
BI-1935 is a potent, selective small molecule inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 7 nM. |
| PC-63244 |
Bractoppin
|
Bractoppin is a potent, small-molecule chemical inhibitor that specific selectively blocks phosphopeptide recognition by the BRCA1 tBRCT domain with binding IC50 of 74 nM. |
| PC-43248 |
EN460
ERO1 inhibitor
|
EN460 is a specific mall molecule inhibitor of endoplasmic reticulum oxidation 1 (ERO1), interacts selectively with the reduced, active form of ERO1α and prevents its reoxidation (IC50=1.9 uM). |
| PC-43219 |
AF38469
Sortilin inhibitor
|
AF38469 is a potent, selective, orally bioavailable Sortilin inhibitor with IC50 of 330 nM. |
| PC-63195 |
RCGD 423
gp130 modulator
|
RCGD 423 (RCGD423) is a small molecule gp130 modulator that prevents articular cartilage degeneration and promotes repair both in vitro and in vivo. |
| PC-42915 |
PFK15
PFKFB3 inhibitor
|
PFK15 (PFK 015) is a potent, selective 6-phosphofructo-2-kinase (PFKFB3) inhibitor with IC50 of 207 nM against recombinant human PFKFB3, displays 100-fold more activity than 3PO. |
| PC-42359 |
Coproporphyrin III
|
Coproporphyrin III is a diffusible small molecule porphyrin excreted by human-associated Propionibacterium spp., induces Staphylococcus aureus aggregation and biofilm formation, also induces S. aureus to form a plasma-independent surface-attached biofilm. |
| PC-42350 |
TPPU
sHE inhibitor
|
TPPU is a potent soluble epoxide hydrolase (sHE) inhibitor with IC50 of 37 nM and 3.7 nM for monkey and human sHE, respectively. |
| PC-63145 |
Verdiperstat
|
Verdiperstat (AZD-3241) is a potent, selective, reversible, orally active myeloperoxidase (MPO) inhibitor with IC50 of 630 nM, >14-fold selectivity over thyroid peroxidase (TPO). |
| PC-63120 |
MIF-IN-3bb
MIF inhibitor
|
MIF-IN-3bb is a potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with Ki of 57 nM. |
| PC-63119 |
Orita-13
MIF inhibitor
|
Orita-13 is potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with Ki of 17 uM. |
| PC-63118 |
ISO-66
MIF inhibitor
|
ISO-66 is a novel, highly stable, small-molecule MIF inhibitor that inhibits MIF tautomerase activity with IC50 of 1.4 uM. |
