| Cat. No. |
Product Name |
Information |
| PC-22222 |
Leflunomide
DHODH inhibitor
|
Leflunomide is a potent dihydroorotate dehydrogenase (DHODH) and pyrimidine synthesis inhibitor with IC50 of 208.5 nM in cell-free human DHODH enzyme inhibition assays. |
| PC-22221 |
HOSU-53 sodium
DHODH inhibitor
|
HOSU-53 sodium is selective and potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 0.95 nM in cell-free human DHODH enzyme inhibition assays. |
| PC-22220 |
HOSU-53
DHODH inhibitor
|
HOSU-53 is selective and potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 0.95 nM in cell-free human DHODH enzyme inhibition assays. |
| PC-22206 |
UNC-CA2-103
TLK2 inhibitor
|
UNC-CA2-103 is a potent, selective tousled like kinase 2 (TLK2) inhibitor with enzyme IC50 of 18 nM, exhibit excellent selectivity over TLK1 (16% inhibition at 0.5 μM). |
| PC-22201 |
NUDT5/NUDT14 inhibitor 9
NUDT5/NUDT14 inhibitor
|
NUDT5/NUDT14 inhibitor 9 is a potent dual cell-active NUDT5/NUDT14 inhibitor with SPR KD of 400 nM for purified human NUDT14 protein. |
| PC-22199 |
BAY R3401
Glycogen phosphorylase inhibitor
|
BAY R3401 is a potent, competive glycogen phosphorylase inhibitor, inhibits muscle glycogen phosphorylase a and b. |
| PC-22198 |
Bay W1807
Glycogen phosphorylase inhibitor
|
BAY W1807 is a potent, competive glycogen phosphorylase inhibitor with Ki of 1.6 nM for rabbit muscle glycogen phosphorylase b (GPb), inhibits muscle glycogen phosphorylase a and b. |
| PC-22184 |
Tacrolimus
FKBP ligand
|
Tacrolimus (FK506) is a macrocyclic lactone that binds to FK506 binding protein (FKBP) to form a complex, inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription, shows immunosuppressive properties. |
| PC-22182 |
RSMI-29
Ricin inhibitor
|
RSMI-29 is a small molecule inhibitor of ricin toxin, specifically targeting ricin toxin A chain (RTA) with binding KD of 0.9 uM, inhibits cytotoxicity of RTA/ricin. |
| PC-22178 |
Trolox
Antioxidant agent
|
Trolox is a water-soluble vitamin E analogue and antioxidant agent, scavenges peroxyl radicals better than vitamin E in sodium dodecyl sulfate micelles and in liposomes. |
| PC-22176 |
SMS121
CD36 inhibitor
|
SMS121 (SMS-121) is a drug-like small molecule inhibitor of the very long/long chain fatty acid transporter CD36 (FAT, scavenger receptor class B member 3/SCARB3) with binding Kd of 5.57 uM. |
| PC-22173 |
Compound 797780-71-3
DJ-1/PARK7 inhibitor
|
Compound 797780-71-3 is a small molevcule, covalent inhibitor of DJ-1 (PARK7), effectively inhibits the proliferation of ACHN cells with IC50 of 12.18 uM, inhibits the Wnt signaling pathway. |
