| Cat. No. |
Product Name |
Information |
| PC-72843 |
RAGE229
RAGE inhibitor
|
RAGE229 (RAGE-229) is a specific antagonist of ctRAGE-DIAPH1 interaction, high potently binds to cytoplasmic tail of RAGE (ctRAGE) with KD of 2 nM. |
| PC-72839 |
BOS-318
Furin inhibitor
|
BOS-318 (BOS318) is a potent, highly selective, cell-permeable furin inhibitor with IC50 of 1.9 nM, Ki of 0.4 nM. |
| PC-72817 |
BACH2 inhibitor compound 8
BACH2/BACH1 inhibitor
|
BACH2 inhibitor compound 8 is a potent, dual BACH2/BACH1 inhibitor. |
| PC-72801 |
HB007
SUMO1 degrader
|
HB007 (HB-007) is a small-molecule degrader of the small ubiquitin-related modifier 1 (SUMO1) with anticancer potency in vitro and in vivo. |
| PC-72788 |
S62798
TAFIa inhibitor
|
S62798 (S 62798) is a highly selective human, mouse and rat TAFIa (Thrombin Activatable Fibrinolysis Inhibitor) inhibitor with IC50 of 11, 270, 178 nM respectively. |
| PC-72775 |
MTDH-SND1 inhibitor C26-A6
MTDH-SND1 inhibitor
|
MTDH-SND1 inhibitor C26-A6 is a specific inhibitor that disrupts the protein-protein interaction (PPI) between MTDH and SND1. |
| PC-72765 |
DC-SX029
SNX10 inhibitor
|
DC-SX029 is a new small-molecule sorting nexin 10 (SNX10) inhibitor (KD=0.935 uM), blocks the SNX10-PIKfyve interaction, decreases TBK1/c-Rel signaling activation. |
| PC-72762 |
CVN424
GPR6 antagonist
|
CVN424 (CVN 424) is a highly potent, selective, brain-penetrant, orally active GPR6 inverse agonist with EC50 of 38 nM. |
| PC-72748 |
PDDC
nSMase2 inhibitor
|
PDDC is the first potent, selective, orally-available, and brain-penetrable nSMase2 (neutral sphingomyelinase 2) inhibitor with pIC50 of 6.57. |
| PC-72745 |
CHD1Li 6.11
CHD1L inhibitor
|
CHD1Li 6.11 is a first in class, orally bioavailable oncogenic CHD1L inhibitor with 3.3 uM (CHD1L-cat enzyme activity). |
| PC-72727 |
T417
PBX1 inhibitor
|
T417 (PBX1 inhibitor T417, TCRS-417) is a novel small molecule compound capable of docking to the interface between PBX1 and its cognate DNA target sequence, potently interferes with the PBX1-DNA interaction with IC50 of 6.58 uM. |
| PC-72720 |
FGF23 inhibitor 13a
FGF23 inhibitor
|
FGF23 inhibitor 13a (FGF23-IN-13a) is a ZINC13407541 analogue with enhanced drug-like properties, inhibits FGF23 with IC50 of 0.14 uM. |
