| Cat. No. |
Product Name |
Information |
| PC-20610 |
Perforin inhibitor 5
Perforin inhibitor
|
Perforin inhibitor 5 is a small molecule Perforin inhibitor, inhibits perforin-induced lysis of Jurkat T-lymphoma cells with IC50 of 1.17 uM. |
| PC-20607 |
Estropipate
OATP1B1 inhibitor
|
Estropipate is a potent, selective inhibitor of organic anion transporting polypeptides 1B1 (OATP1B1) with IC50 of 0.05 and 0.12 uM for human and cynomolgus monkey OATP1B1, respecitvely. |
| PC-20595 |
NS5806
cTnC activator
|
NS5806 is a small molecule cardiac troponin (cTnC) activator, binds to Ca2+-saturated cChimera with Kd of 7.6 uM, stabilizes active troponin, significantly increases the ATPase activity of cardiac myofibrils in a dose-dependent manner. |
| PC-20581 |
RX-105
|
RX-105 (RX105) is a small molecule inhibitor of protein interaction with glycosaminoglycans (SMIGs) with anti-inflammatory properties, binds directly to glycosaminoglycans (GAGs). |
| PC-20580 |
RX-207
|
RX-207 (RX207) is a small molecule inhibitor of protein binding to glycosaminoglycans (SMIGs), inhibits protein binding to glycosaminoglycans (GAGs), inhibits inflammatory neutrophil adhesion and activity in vitro and in vivo. |
| PC-20569 |
ERAD inhibitor CP26
Dislocation inhibitor
|
ERAD inhibitor CP26 (NSC26112) is a small molecule inhibitor of Hrd1 complex-mediated dislocation, inhibits NHK dislocation in HeLa cells with IC50 of 4.45 μM in the drGFP assays, shows broad-spectrum anti-flavivirus activity. |
| PC-20567 |
PF-04859989
Kynurenine aminotransferase II inhibitor
|
PF-04859989 is a potent, selective, brain-penetrant, irreversible inhibitor of human and rat KAT II (kynurenine aminotransferase II) with IC50 of 23 and 263 nM, respectively. |
| PC-20557 |
GKI-1
MASTL inhibitor
|
GKI-1 (Greatwall Kinase Inhibitor-1) is a specific small-molecule inhibitor of MASTL (microtubule-associated serine/threonine kinase-like, Greatwall/GWL) with IC50 of 10.2 uM. |
| PC-20555 |
MKI-1
MASTL inhibitor
|
MKI-1 (MASTL inhibitor 1) is a small molecule MASTL (microtubule-associated serine/threonine kinase-like, Greatwall/GWL) inhibitor with IC50 of 9.9 uM. |
| PC-20554 |
YQ456
Myoferlin inhibitor
|
YQ456 (YQ-456) is a specific small molecule inhibitor of Myoferlin (MYOF) with high binding affinity (KD=37 nM) to MYOF‐C2D domain, suppresses colorectal cancer invasion in vitro with IC50 of 110 nM. |
| PC-20507 |
SRC-3 inhibitor SI-12
SRC-3 inhibitor
|
SRC-3 inhibitor SI-12 is a potent small molecule inhibitor of steroid receptor coactivator (SRC-3), inhibits MCF-7 breast cancer cell growth with IC50 of 7 nM, exhibits low hERG activity (IC50=1.13 uM). |
| PC-20506 |
SRC-3 inhibitor SI-10
SRC-3 inhibitor
|
SRC-3 inhibitor SI-10 is a potent small molecule inhibitor of steroid receptor coactivator (SRC-3), inhibits MCF-7 breast cancer cell growth with IC50 of 8.5 nM, exhibits low hERG activity (IC50>10 uM). |
