| Cat. No. |
Product Name |
Information |
| PC-73396 |
CB253
r(G4C2)exp inhibitor
|
CB253 is a small molecule that selectively binds the hairpin form of r(G4C2)exp, inhibiting mechanisms that drive c9ALS/FTD pathobiology. |
| PC-73386 |
PRG-A01
SOD1 inhibitor
|
PRG-A01 is a chemical inhibitor against SOD1 misfolding and aggregation, inhibits the neuronal cell death caused by mutant-SOD1 overexpression. |
| PC-73320 |
FHD-286
BRG1/BRM inhibitor
|
FHD-286 (FHD286) is a highly potent, selective, allosteric and orally available inhibitor of BRG1 (SMARCA4)/BRM (SMARCA2), dual BRM/ BRG1 inhibitor. |
| PC-73242 |
DS-3801b
GPR38 agonist
|
DS-3801b is a potent, selective, non-macrolide GPR38 agonist for the treatment of functional gastrointestinal disorders. |
| PC-73232 |
Dynein inhibitor 20
Dynein inhibitor
|
Dynein inhibitor 20 is a small moelcule inhibitor of S. cerevisiae dynein by engaging the regulatory ATPase sites in AAA3 and AAA4 domains. |
| PC-73185 |
Hi 76-0079
HSL inhibitor
|
Hi 76-0079 (NNC0076-0079) is a specfic, small molecule inhibitor of hormone-sensitive lipase (HSL) with IC50 of 0.11 uM. |
| PC-73149 |
DLin-MC3-DMA
|
DLin-MC3-DMA is an ionizable amino lipid (apparent pKa = 6.44) that has been used in combination with other lipids in the formation of lipid nanoparticles. |
| PC-73139 |
ASN 90
O-GlcNAcase inhibitor
|
ASN90 is a potent, selective, substrate-competitive O-GlcNAcase (OGA) inhibitor with IC50 of 10.2 nM. |
| PC-73138 |
KVD900
Plasma kallikrein inhibitor
|
Sebetralstat (KVD900) is a potent,selective, competitive and reversible inhibitor of human plasma kallikrein (PKa) enzyme with Ki of 3.02 nM. |
| PC-73136 |
Naphthyridine-azaquinolone
Slipped-CAG DNA binder
|
Naphthyridine-azaquinolone (NA) is a specific small molecule that specifically binds slipped-CAG DNA intermediates of expansion mutations. |
| PC-73129 |
HG106
SLC7A11 inhibitor
|
HG106 (HG 106) is a potent, selective SLC7A11 inhibitor, selectively kills KRAS-mutant lung adenocarcinoma (LUAD) cells. |
| PC-73111 |
S-181
GCase activator
|
S-181 (S 181) is a specific small-molecule activator (modulator) of β-glucocerebrosidase (GCase) with AC50 of 1.49 uM and a maximum activation of 780%. |
