| Cat. No. |
Product Name |
Information |
| PC-20821 |
PKA inhibitor H89
PKA inhibitor
|
PKA inhibitor H89 (H-89 dihydrochloride) is a potent, selective cAMP-dependent protein kinase A (PKA) inhibitor with IC50 of 48 nM, weakly inhibits PKG, PKC, casein kinases. |
| PC-20817 |
KZR-8445
Sec61 inhibitor
|
KZR-8445 (KZR8445) is a cyclic depsipeptide, client-selective Sec61 inhibitor with IC50 of 100 nM, targets the Sec61 translocon and selectively modulate Sec61-mediated protein biogenesis. |
| PC-20794 |
CK147
Sec61 inhibitor
|
CK147 (CK-147) is a potent CD4 down-modulator with IC50 of 63 nM, inhibits Sec61-dependent cotranslational translocation of huCD4 in vitro. |
| PC-20790 |
GO-203
MUC1-C inhibitor
|
GO-203 (GO203) is a cell-penetrating peptide inhibitor of mucin-1-cycloplasmic C-terminal subunit (MUC1-C), blocks homodimerization of the MUC1-C subunit required for nuclear translocation and downstream signaling. |
| PC-20788 |
NSC348884
Nucleophosmin inhibitor
|
NSC348884 is a small molecule nucleophosmin (NPM) inhibitor, disrupts the formation of dimers and inhibits aberrant NPM functionin cancer cells. |
| PC-20785 |
Sodium phytate
|
Sodium phytate (Phytic acid sodium salt, InsP6 sodium) is the most abundant inositol phosphate in cells, is a strong inhibitor of iron absorption from fortified foods, has antioxidant and anti-diabetic properties. |
| PC-20779 |
HP661
OXPHOS inhibitor
|
HP661 is a potent, and selective oral complex I OXPHOS inhibitor with 76% inhibition at 1u M in H460 cells using electron flow assays, inhibits high-OXPHOS H460 cell viability with IC50 of 5 nM. |
| PC-20754 |
BACH1 inhibitor M2
Bach1 inhibitor
|
BACH1 inhibitor M2 is a small molecule inhibitor of the transcription factor BTB and CNC homolog 1 (BACH1), inhibits AFB1-induced porcine and human cell death in vitro and AFB1-induced symptoms of weight loss and liver injury in vivo. |
| PC-20748 |
Org 214444-0
FSHR agonist
|
Org 214444-0 is a highly potent, selective, allosteric agonist of follicle stimulating hormone receptor (FSHR) with EC50 of 2.0/1.2 nM (human/rat FSHR) in cell-based assays. |
| PC-20719 |
A1120
RBP4 inhibitor
|
A1120 is a high affinity, non-retinoid ligand for retinol-binding protein 4 (RBP4) with Ki of 8.3 nM, disrupts the interaction between RBP4 and its binding partner transthyretin (TTR). |
| PC-20718 |
BPN-14136
RBP4 inhibitor
|
BPN-14136 is a potent, selective and non-retinoid RBP4 antagonist with SPA IC50 of 12.8 nM and HTRF IC50 of 43.6 nM. |
| PC-20714 |
ME-143
NADH oxidase inhibitor
|
ME-143 (NV-143) is a second-generation tumor-specific NADH oxidase inhibitor, binds to purified recombinant ENOX2 with Kd value of 43 nM, shows broad activity against human cancers in vitro and in vivo. |
