| Cat. No. |
Product Name |
Information |
| PC-42072 |
BAPTA
Mg2+ chelator
|
BAPTA is a cell-permeant, calcium-specific chelator with high selectivity over Mg2+. |
| PC-45623 |
GW4869
nSMase inhibitor
|
GW-4869 (GW4869, GW 4869) is a cell-permeable, potent, specific, non-competitive inhibitor of neutral sphingomyelinase (nSMase) with IC50 of 1 uM. |
| PC-42082 |
TPEN
LIN28 inhibitor
|
TPEN (TPEDA) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM, also is a specific cell-permeable heavy metal chelator. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-24771 |
Kaempferol
MARK4 inhibitor
|
Kaempferol is a natural MARK4 inhibitor with IC50 of 11.54 uM, also inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK. |
| PC-24758 |
CD39 inhibitor Compound 338
CD39 inhibitor
|
CD39 inhibitor compound 338 is a potent, selective nucleotidase NTPDase1 (CD39) inhibitor with IC50 of 68.7 nM, weakly inhibits NTPDase 2 and NTPDase 3, with IC50 values of 975.9 nM and 715.9 nM, respectively. |
| PC-24752 |
LOXL2-IN-1 tosylate
LOXL2 inhibitor
|
LOXL2-IN-1 tosylate is a selective and orally active lysyl oxidase-like 2 (LOXL2) inhibitor with IC50 of <300 nM, compound 22 extracted from patent WO2017136870A1. |
| PC-24751 |
LOXL2-IN-1
LOXL2 inhibitor
|
LOXL2-IN-1 is a selective and orally active lysyl oxidase-like 2 (LOXL2) inhibitor with IC50 of <300 nM, compound 22 extracted from patent WO2017136870A1. |
| PC-24750 |
LOX-IN-4
pan-LOX inhibitor
|
LOX-IN-4 is a potent lysyl oxidase (LOX) inhibitor, Compound 112 extracted from patent WO2017136870A1. |
| PC-24749 |
PXS-4787 hydrochloride
pan-LOX inhibitor
|
PXS-4748 hydrochloride (PXS4748) is a potent, selective and irreversible pan-lysyl oxidase (pan-LOX) inhibitor with IC50 of 2.0 uM and 3.2/0.6/1.4/0.2 uM for bovine (aorta) LOX and rh LOXL1/2/3/4, respectively. |
| PC-24748 |
PXS-6302 hydrochloride
pan-LOX inhibitor
|
PXS-6302 hydrochloride (PXS6302) is a potent, irreversible pan-lysyl oxidase (pan-LOX) inhibitor with IC50 of 3.7 uM and 3.4/0.4/1.5/0.3 uM for bovine (aorta) LOX and rh LOXL1/2/3/4, respectively. |
| PC-24743 |
Kifunensine
alpha-mannosidase I inhibitor
|
Kifunensine (FR-900494) is a potent inhibitor of glycoprotein processing mannosidase I (alpha-mannosidase I) with IC50 of 20-50 nM, inactive toward the plant mannosidase II, kifunensine also inhibits the Golgi mannosidase I in rat liver microsomes. |
