| Cat. No. |
Product Name |
Information |
| PC-35462 |
ADX-102
|
ADX-102 (Reproxalap, NS-2) is a novel small molecule immunomodulator that covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal, which have been shown to mediate inflammatory pain. |
| PC-35460 |
ATR-101 free base
|
ATR-101 (PD-132301, Nevanimibe) is a selective and potent inhibitor of ACAT1 with IC50 of 52 nM. |
| PC-35451 |
TRX-818 sodium
|
TRX-818 sodium (Foslinanib sodium ) is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities, induces cancer cell apoptosis and inhibits cancer cell proliferation. |
| PC-35450 |
Foslinanib
|
Foslinanib (TRX-818) is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities, induces cancer cell apoptosis and inhibits cancer cell proliferation. |
| PC-35441 |
Cimlanod
|
Cimlanod is a second-generation nitroxyl (HNO) donor.. |
| PC-35430 |
BIO124
|
BIO124 (BIO-124) is a modest inhibitor of the PICK1-GluA2 interaction with IC50 of 0.51 uM in FP assays, binds to the PDZ domain of PICK1.. |
| PC-35415 |
Desmethyl dabrafenib
|
Desmethyl dabrafenib (GSK2167542, Dabrafenib metabolite M8) is the desmethyl- metabolic byproduct of Dabrafenib, ameliorates developmental pathologies of Kabuki Syndrome in vivo.. |
| PC-35412 |
GAK inhibitor 49
|
GAK inhibitor 49 is a potent, selective, ATP-competitive inhibitor of cyclin G-associated kinase (GAK, cell IC50=56 nM) with favourable NAK family selectivity (AAK1, STK16, BMP2K). |
| PC-35410 |
IGS-1.76
|
IGS-1.76 is a small molecule inhibitor of human NCS-1/Ric8a interaction with affinity of 1.25 uM (hNCS-1). |
| PC-35371 |
Edonerpic maleate
|
Edonerpic maleate (T-817MA) is a neurotrophic agent that can protects neuronal cells and modifies their morphology. |
| PC-35339 |
SGN-2FF
|
SGN-2FF (2-Fluorofucose, SGD-2083) is an orally bioavailable small molecule inhibitor of glycoprotein fucosylation, demonstrates encouraging preclinical antitumor activity in mouse models. |
| PC-35330 |
CCG-222740
|
CCG-222740 (CCG222740) is a pharmacological inhibitor of MRTF/SRF signalling, shows greater inhibitory effect on MRTF/SRF target genes than MRTF-A inhibitor CCG-203971, with IC50 of 5 uM in fibroblast-mediated collagen contraction assay. |
