| Cat. No. |
Product Name |
Information |
| PC-26995 |
SIPI11594
MPC inhibitor
|
SIPI11594 is a small molecule mitochondrial pyruvate carrier (MPC) inhibitor, shows cellular lactate production-enhancing activity, significantly accelerates hair regrowth and anagen entry. |
| PC-26982 |
Zearalenone
Endocrine disruptor
|
Zearalenone (Mycotoxin F2, Toxin F2) is a potent endocrine disruptor that poses serious health risks through reproductive toxicity. |
| PC-26955 |
UCM-1336
ICMT inhibitor
|
UCM-1336 is a potent, selective isoprenylcysteine carboxylmethyltransferase (ICMT) inhibitor with IC50 of 2 uM. |
| PC-26951 |
AGPS-IN-1
AGPS inhibitor
|
AGPS-IN-1 (AGPS inhibitor 2i) is a small molecule inhibitor of alkylglyceronephosphate synthase (AGPS), decreases ether lipids, cell migration and survival, specifically impairs EMT through E-cadherine, Snail, Mmp2 modulation. |
| PC-26941 |
NCGC00138783 TFA
CD47/SIRPα inhibitor
|
NCGC00138783 TFA is a selective inhibitor targeting CD47/SIRPα axis with IC50 of 50 µM, directly blocks the interaction between CD47 and SIRPα. |
| PC-26940 |
NCGC00138783
CD47/SIRPα inhibitor
|
NCGC00138783 is a selective inhibitor targeting CD47/SIRPα axis with IC50 of 50 µM, directly blocks the interaction between CD47 and SIRPα. |
| PC-26939 |
NCGC00092410
GCase inhibitor
|
NCGC00092410 is a potent, selective and nonsugar glucocerebrosidase (GC, GCase) inhibitor with IC50 of 31 nM. |
| PC-26936 |
NCGC00685960
NNMT inhibitor
|
NCGC00685960 is a highly potent, specific Nicotinamide N-methyltransferase (NNMT) inhibitor with IC50 of <10 nM, increases H3K27 trimethylation levels in ovarian cancer cells and inhibits α-SMA expression in NNMT-expressing ovarian fibroblasts, has potent antitumor activity. |
| PC-26933 |
β-actin inhibitor C25
β-actin inhibitor
|
β-actin inhibitor C25 is potent, selective and covalent inhibitor of beta-actin (β-actin), does not target α- or γ-actin, inhibits β-Actin polymerization to disrupt the actin cytoskeleton and lead to cell death in143B cells (IC50=15 nM), selectively and covalently binds to Cys272 in β-actin. |
| PC-26922 |
GPR52 agonist R-185
GPR52 agonist
|
GPR52 agonist R-185 is a potent, selective, brain permeable and orally available GPR52 agonist with EC50 of 26 nM, significantly inhibits MK-801-induced hyperlocomotor behaviors in zebrafish larvae and mice. |
| PC-26921 |
GPR52 agonist 1
GPR52 agonist
|
GPR52 agonist 1 is a potent, BBB- penetrant and orally available agonist of orphan G-protein-coupled receptor 52 (GPR52) with pEC50 of 7.53, suppresses methamphetamine-induced hyperactivity in vivo. |
| PC-26920 |
B0045
VprBP inhibitor
|
B0045 is a specific, second-generation inhibitor of DCAF1 (Vpr-binding protein, VprBP), blocks VprBP-mediated H2AT120p and reactivates growth regulatory genes, resulting in a significantly lower proliferative capacity of prostate cancer cells. |
