| Cat. No. |
Product Name |
Information |
| PC-61463 |
VPC-18005
|
VPC-18005 (VPC18005) is a novel small molecule ERG (ETS-related gene) antagonist that inhibits ERG-induced transcription and interacts directly with the ERG-ETS domain, disrupts the ERG binding to DNA (Kd=250 uM). |
| PC-61428 |
Ibiglustat
|
Ibiglustat (Venglustat, Genz-682452) is an orally active, selective and potent Glucosylceramide synthase (GCS) inhibitor with central nervous system (CNS) access. |
| PC-61427 |
EXEL-0346
GCS inhibitor
|
EXEL-0346 (EXEL0346) is a novel potent, orally active Glucosylceramide synthase (GCS) inhibitor with IC50 of 2 nM. |
| PC-61423 |
Myriocin
|
Myriocin (ISP-1) is an amino fatty acid antibiotic that is 10- to 100-fold more potent than cyclosporin A as an immunosuppressive agent of the immune response in vitro and in vivo. |
| PC-61399 |
Setafrastat
|
Setafrastat is a small molecule hair growth stimulator. |
| PC-61393 |
Parimifasor
ATPase modulator
|
Parimifasor (LYC-30937-EC, LYC30937) is an orally bioavailable, enteric-coated ATPase modulator as a gut-directed therapy for the treatment of inflammatory bowel disease (IBD). |
| PC-61340 |
PF-06928215
cGAS inhibitor
|
PF-06928215 (PF06928215) is a high affinity Cyclic GMP-AMP synthase (cGAS) inhibitor with Kd of 200 nM, IC50 of 4.9 uM. |
| PC-61320 |
RK-33
|
RK-33 is a first-in-class small molecule inhibitor of RNA helicase DDX3, binds specifically to DDX3, but not to the closely related proteins DDX5 and DDX17. |
| PC-61316 |
Teglicar
|
Teglicar (ST-1326) is a potent, selective and reversible inhibitor of liver carnitine palmitoyl-transferase 1 (L-CPT1) with IC50 of 0.68 uM, Ki of 0.36 uM. |
| PC-61262 |
TB-03
Grb2 SH2 inhibitor
|
TB-03 is a small molecule Grb2 SH2 domain binding antagonist that synergistically enhances inhibition of K562 leukemia cell proliferation by imatinib (CI=0.774). |
| PC-61245 |
DC_AC50
|
DC_AC50 (DCAC50) is a small molecule that inhibits the human copper chaperones Atox1 and CCS (Kd=6.8 and 8.2 uM), blocks copper trafficking and significantly attenuates cancer cell proliferation. |
| PC-61244 |
STOML3 inhibitor OB-1
|
STOML3 inhibitor OB-1 is a small-molecule inhibitor of STOML3 oligomerization that reverses pathological mechanical hypersensitivity in vivo. |
