| Cat. No. |
Product Name |
Information |
| PC-63118 |
ISO-66
MIF inhibitor
|
ISO-66 is a novel, highly stable, small-molecule MIF inhibitor that inhibits MIF tautomerase activity with IC50 of 1.4 uM. |
| PC-63111 |
CE3F4
|
CE3F4 is a potent, noncompetitive EPAC1 inhibitor that blocks EPAC1-induced Rap1 activation both in cell-free systems and in intact cells and did not influence protein kinase A holoenzyme activity. |
| PC-63109 |
ESI-05
|
ESI-05 is a potent EAPC2-specific antagonist that inhibits cAMP-mediated EPAC2 GEF activity with apparent IC50 of 0.43 uM. |
| PC-63107 |
NSC 45576
EPAC inhibitor
|
NSC 45576 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor with IC50 of 1.7 uM. |
| PC-63105 |
HJC 0726
|
HJC 0726 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor, inhibits cAMP-mediated EPAC2 GEF activity with IC50 of 1.0 uM. |
| PC-62954 |
K-604
|
K-604 is a potent, selective and competitive ACAT-1 inhibitor with IC50 of 0.45 uM for human ACAT-1, displays 229-fold selectivity over ACAT-2. |
| PC-62880 |
DDD85646
NMT1/NMT2 inhibitor
|
DDD 85646 is a potent, specific, dual N-Myristoyltransferase NMT1/NMT2 inhibitor with IC50 of 17 nM/22 nM respectively. |
| PC-62875 |
STK16-IN-1
|
STK16-IN-1 is a potent, highly selective ATP competitive STK16 inhibitor with IC50 of 0.295 uM, displays excellent selectivity across the kinome. |
| PC-62859 |
SB1301
Lin28 inhibitor
|
SB1301 (Lin28-IN-1) is a small-molecule inhibitor disrupting the protein-RNA interaction of LIN28 and Let-7 with FRET IC50 of 4 uM. |
| PC-62825 |
CCG-203971
|
CCG-203971(CCG203971) is a potent Rho/MKL1/SRF transcriptional pathway inhibitor, suppresses PC-3 cell migration in scratch wound assays (IC50=4.2 uM), blocks nuclear localization and activity of MRTF-A in SK-Mel-147 cells. |
| PC-62753 |
Sepin-1
|
Sepin-1 is a small molecule, noncompetitive separase inhibitor with IC50 of 14.8 uM. |
| PC-62745 |
DB2115
PU.1 inhibitor
|
DB2115 is a small-molecule transcription factor PU.1 inhibitor abrogating DNA binding by PU.1 with Kd of 1.0 nM. |
