| Cat. No. |
Product Name |
Information |
| PC-25446 |
G4451
GPR31 inhibitor
|
G4451 is a specific small molecule inhibitor of GPR31, inhibits the GPR31-Gαi3 interaction by targeting the GPR31 conformational transition, effectively blocked MASH progression. |
| PC-25445 |
RGX-202
SLC6A8 inhibitor
|
RGX-202 (RGX202, Ompenaclid, β-guanidinoproprionic acid) is an oral small-molecule creatine mimetic inhibitor of creatine transporter SLC6A8, inhibits cellular creatine import and suppresses intracellular phosphocreatine, creatine, and ATP levels, exhibits broad antitumor activity against diverse primary and metastatic CRCs. |
| PC-25281 |
KI-DX-014
DDX21 inhibitor
|
KI-DX-014 is a specific small-molecule compound capable of inhibiting the interaction of DDX21 with RNA with IC50 of 3.31 uM, directly binds to DDX21-C-terminal domain (HC+CTD) with Kd of 15.9 uM, allosterically attenuates DDX21 ATPase activity. |
| PC-25222 |
ASS1 inhibitor C-01
ASS1 inhibitor
|
ASS1 inhibitor C-01 is a small molecule inhibitor of argininosuccinate synthetase 1 (ASS1), binds to ASS1 directly with SPR Kd of 18.8 nM. |
| PC-25184 |
JX-078
LAT1 inhibitor
|
JX-078 is a potent, selective inhibitor of L-type amino acid transporters LAT1 (SLC7A5), inhibits [3H]-L-leucine uptake into HT-29 cells with IC50 of 121 nM, >10-fold selective over in LAT2. |
| PC-25146 |
BI033
BACH1 inhibitor
|
BI033 is a selective small-molecule BTB and CNC homology 1 (BACH1) inhibitor, specifically binds to BACH1 WT with Kd of 9.0 uM, significantly upregulates HO-1 mRNA and protein expression. |
| PC-25105 |
DEL-S1
SLIT2/ROBO1 inhibitor
|
DEL-S1 is a first-in-class small molecule that binds to SLIT2 and disrupts its interaction with ROBO1 with IC50 of 68.8 uM in TR-FRET assays. |
| PC-25013 |
TREM2 agonist C1
TREM2 agonist
|
TREM2 agonist C1 is a structural analog of VG-3927 and small molecule agonist of triggering receptor expressed on myeloid cells 2 (TREM2) with KD of 71.36 uM in MST assays. |
| PC-24950 |
Eloralintide sodium
Amylin receptor agonist
|
Eloralintide sodium (LY3841136) is a selective amylin mimetic and long acting amylin receptor (AMYR) agonist, binds to amylin receptors with high selectivity from calcitonin receptors. |
| PC-24949 |
Eloralintide
Amylin receptor agonist
|
Eloralintide (LY3841136) is a selective amylin mimetic and long acting amylin receptor (AMYR) agonist, binds to amylin receptors with high selectivity from calcitonin receptors. |
| PC-24839 |
NGI-186
Oligosaccharyltransferase inhibitor
|
NGI-186 is a potent, small molecule inhibitor of oligosaccharyltransferase (OST) with IC50 of 0.06 uM. |
| PC-24837 |
NGI-189
Oligosaccharyltransferase inhibitor
|
NGI-189 is a potent, small molecule inhibitor of oligosaccharyltransferase (OST) with IC50 of 0.09 uM. |
