| Cat. No. |
Product Name |
Information |
| PC-72746 |
Sari 59-801
|
SaRI 59-801 is an orally effective hypoglycemic compound, decreases blood glucose in several species and to elevate plasma insulin in rats and mice. |
| PC-72738 |
S-Y048
OXE receptor antagonist
|
S-Y048 ((S)-Y048) is a highly potent, selective OXE receptor antagonist, inhibits 5‐oxo‐ETE‐induced calcium mobilization in human neutrophils with pIC50 of 10.8 (20 pM). |
| PC-72667 |
UNC10245131
CIB1 inhibitor
|
UNC10245131 (UNC 10245131) is a potent, selective cyclic peptide inhibitor of calcium and integrin binding protein 1 (CIB1) with ITC Kd of 6.17 nM. |
| PC-72579 |
SHMT inhibitor SHIN2
SHMT inhibitor
|
SHMT inhibitor SHIN2 ((+) SHIN2) is a potent, selective, mammalian SHMT1/2 inhibitor with antileukemic effect in vivo. |
| PC-72568 |
MBD2 inhibitor APC
MBD2 inhibitor
|
MBD2 inhibitor APC (APC) is a small molecule inhibitor targeting an intrinsically disordered protein region (IDPR) of MBD2 with antimetastatic activity, inhibits DOT-mediated PPI of MBD2, efficiently disrupts MBD2 interaction with p66α with IC50 of 1.03 uM (FRET). |
| PC-72567 |
MBD2 inhibitor ABA
MBD2 inhibitor
|
MBD2 inhibitor ABA (ABA) is a small molecule inhibitor targeting an intrinsically disordered protein region (IDPR) of MBD2 with antimetastatic activity, inhibits DOT-mediated PPI of MBD2, efficiently disrupts MBD2 interaction with p66α with IC50 of 1.4 uM (FRET). |
| PC-72563 |
CC260
PI5P4Kα/β inhibitor
|
CC260 (CC-260) is a potent, selective inhitor of PI5P4Kα/β with Ki of 40/30 nM, respectively. |
| PC-72554 |
PAX inhibitor BG1
PAX inhibitor
|
PAX inhibitor BG1 (PAX-IN-BG1) is a small molecule that attenuate Pax-2 transactivation ability with IC50 of 1.5 uM. |
| PC-72550 |
Compound R80
CTPS1 inhibitor
|
Compound R80 (CTPS1-IN-R80) is a potent, selective inhibitor of CTPS1 (cytidine triphosphate synthase 1) with IC50 of 8.4 nM in RapdFire MS assays, >100-fold selectivity over CTPS2 (IC50=4.3 uM). |
| PC-72547 |
SG-094
TPC2 inhibitor
|
SG-094 (SG094) is a specific cytostatic two-pore channel 2 (TPC2) inhibitor with IC50 of 8.3 uM (TPC2 activator TPC2-A1-P inhibition), shows antiproliferative effect on RIL175 cells with IC50 of 3.7 uM. |
| PC-72546 |
SBI-0802936
complex I inhibitor
|
SBI-0802936 (SBI 0802936) is an analog of SMIP004-7, inhibits NADH:ubiquinone oxidoreductase (complex I), 4-6 times more potently than SMIP004-7, acting in the same uncompetitive fashion as SMIP004-7. |
| PC-72545 |
SMIP004-7
complex I inhibitor
|
SMIP004-7 is a small molecule inhibitor of mitochondrial respiration with selective in vivo anti-cancer activity, targets drug-resistant cancer cells with stem-like features by inhibiting NADH:ubiquinone oxidoreductase (complex I). |
