| Cat. No. |
Product Name |
Information |
| PC-26717 |
HF-125
TRIB2 inhibitor
|
HF-125 is a potent, selective small molecule inhibitor of Tribbles 2 (TRIB2), directly binds to destabilize and degrade TRIB2 proteins involving proteasomes and is effective both in vitro and in vivo. |
| PC-26684 |
LMT328
Sulfiredoxin inhibitor
|
LMT328 (LMT-328) is a potent inhibitor of sulfiredoxin (Srx) with IC50 of 6.7 uM. |
| PC-26615 |
ERG245
BCAT1 inhibitor
|
ERG245 is a potent, selective BCAT1 inhibitor with IC50 of 0.5 nM for recombinant human BCAT1 (rhBCAT1), >2000-fold selectivity for BCAT1 over BCAT2. |
| PC-26468 |
NCGC00238624
GALK1 inhibitor
|
NCGC00238624 is a highly selective galactokinase (GALK1) inhibitor with IC50 of 7.69 and 13.67 uM against the human and mouse recombinant GALK1, respectively, lowers gal-1P levels in primary fibroblast cells derived from patients with classic galactosemia. |
| PC-26467 |
GALK1-IN-1
GALK1 inhibitor
|
GALK1-IN-1 is an effective ATP-competitive galactokinase 1 (GALK1) inhibitor with IC50 of 1 uM in luminescence GALK-ATP-depletion assay. |
| PC-26416 |
NFYi5
NF-Y inhibitor
|
NFYi5 is a specific small molecule inhibitor of Nuclear Transcription Factor-Y (NF-Y), inhibits NF-Y-dependent transcriptional activity, dose dependently inhibits activity of the NF-Y reporter in both human and rat cardiac fibroblasts with IC50 of 19.95 and 12.73 uM respectively. |
| PC-26266 |
CVN14
CD38 inhibitor
|
CVN14 is a potent, selective, uncompetitive and brain-penetrant CD38 inhibitor with IC50 of 19 nM and 2 nM for human and mouse CD38 respectively. |
| PC-26205 |
CN-0928
PCBP2 inhibitor
|
CN-0928 is a specific small molecule inhibitor of poly(C)-binding protein 2 (PCBP2), mitigates AD pathology by inhibiting PCBP2 condensation. |
| PC-26112 |
GSK902056A
PKN3 inhibitor
|
GSK902056A is a highly potent inhibitor of serine/threonine kinase PKN3 with Kdapp of 1 nM, potently engaged PKN3 in cells with IC50 of 79 nM. |
| PC-26109 |
SOD1 lactylation inhibitor ZL-01
SOD1K123la inhibitor
|
SOD1 lactylation inhibitor ZL-01 is a potential specifi inhibitor of csuperoxide dismutase 1 (SOD1) lactylation at lysine 123 (SOD1K123la), effectively reduces the SOD1K123la level and increases SOD1 activity. |
| PC-26108 |
Py-Pip
Neurolysin activator
|
Py-Pip is a nonpeptide small molecule activator of Neurolysin (Nln), enhances the activity of peptidase neurolysin. |
| PC-26087 |
MKV3
Cu+-ATPases inhibitor
|
MKV3 is a specific, first-in-class, broad spectrum inhibitor of Cu-transporting P-type ATPases targeting P1B-type copper ATPases, binds within the Cu+ entry pocket, thereby blocking Cu+ delivery to the intramembranous transport site, dependently decreases Cu+-stimulated ATPase activity with IC50 of 130 nM for Escherichia coli Cu+-ATPase CopA (EcCopA). |
